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Negative affect is associated with development and persistence of chemical intolerance: a prospective
Sine Skovbjerg1, Karl Bang Christensen2, Jeanette Frost Ebstrup1
1The Research Centre for Prevention and Health, Capital Region, Copenhagen, Denmark.
Journal of Psychosomatic Research
|March 12, 2015
Summary
Negative affect, or negative emotions, may increase the risk of developing or continuing to experience chemical intolerance (CI). This finding suggests a link between psychological state and physical health reactions to common chemicals.
Area of Science:
- Environmental Health
- Psychosomatic Medicine
- Epidemiology
Background:
- Chemical intolerance (CI) involves adverse health effects from common airborne chemicals.
- The role of negative affect in CI development and persistence requires further investigation.
Purpose of the Study:
- To explore the hypothesized role of negative affect in the development and persistence of CI.
- To examine baseline negative affect as a risk factor for CI development and persistence in a general population.
Main Methods:
- A longitudinal study of a general population sample (aged 19-72) was conducted over two time points (2006-2008 and 2011-2012).
- Participants were classified based on self-reported reactions to chemicals, related symptoms, and daily life adjustments.
- Statistical analysis examined baseline negative affect as a predictor of CI development and persistence.
Main Results:
- Chemical intolerance (CI) showed persistence, with 69.4% of baseline CI cases reporting CI at follow-up.
- A significant proportion (15.5%) of participants without baseline CI developed CI within 5 years.
- Baseline negative affect was positively and significantly associated with both the development and persistence of CI.
Conclusions:
- Chemical intolerance (CI) reports are often persistent over time.
- A notable percentage of individuals initially without CI developed it over the 5-year study period.
- Negative affect appears to be a potential risk factor for chemical intolerance (CI).
Keywords:
Chemical intoleranceEpidemiologyLongitudinal studyMultiple chemical sensitivityNegative affectMore Related Videos
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