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Updated: Apr 16, 2026

Generation and Expansion of Human Cardiomyocytes from Patient Peripheral Blood Mononuclear Cells
Published on: February 12, 2021
Continued expansion of the Heart Team concept
Jonathan J Passeri1, Serguei Melnitchouk, Igor F Palacios
1Division of Cardiology, Corrigan Minehan Heart Center, Massachusetts General Hospital & Harvard Medical School, Yawkey Building, Suite 5700, Boston, MA 02114, USA.
Insights
The multidisciplinary Heart Team approach improves cardiovascular disease treatment. This collaborative model, proven in other fields, is becoming the standard of care for complex heart conditions.
Area of Science:
- Cardiovascular Medicine
- Medical Team-Based Care
Background:
- The Heart Team approach is gaining traction in cardiovascular medicine.
- Similar team-based models are established in oncology and transplantation.
- Complex cardiovascular diseases present challenging therapeutic decisions due to numerous options.
Purpose of the Study:
- To highlight the growing interest and evidence supporting the Heart Team approach.
- To discuss the increasing complexity of cardiovascular disease management.
- To emphasize the potential of the Heart Team as a future standard of care.
Main Methods:
- Literature review on the Heart Team approach in cardiovascular disease.
- Analysis of the benefits of multidisciplinary collaboration.
- Discussion of the evolution of treatment strategies.
Main Results:
- The Heart Team approach has demonstrated significant merit in managing complex cardiovascular diseases.
- Evidence suggests improved outcomes and decision-making through collaboration.
- The model's adaptability is noted, with variations in composition and implementation.
Conclusions:
- The multidisciplinary Heart Team approach is highly beneficial for complex cardiovascular conditions.
- This collaborative model is poised to become the standard of care in cardiology.
- Further integration of the Heart Team is recommended for optimal patient management.
Abstract:
The concept of a multidisciplinary Heart Team approach to treating cardiovascular disease has garnered increasing interest in recent years. This team-based approach has been a cornerstone of practice in other medical fields, such as oncology and solid organ transplantation. Advances in technology and new therapeutic strategies now offer multiple treatment options to patients with complex coronary artery or valvular heart disease, making therapeutic decision-making more challenging. There is a growing literature that use of a Heart Team for management of these complex cardiovascular diseases has demonstrated great merit. While the composition and implementation of Heart Team will vary, this multidisciplinary team-based approach will become the standard of care in cardiovascular medicine in the future.
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