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[Crohn's disease: a controversy]

Ruben J Colman1

  • 1The University of Chicago Medicine, Inflammatory Bowel Disease Center, Chicago, Verenigde Staten.

Nederlands Tijdschrift Voor Geneeskunde
|March 12, 2015
PubMed

Insights

Burril B. Crohn

Area of Science:

  • Gastroenterology
  • Medical History

Background:

  • The naming of Crohn's disease is linked to a 1932 publication by Burril B. Crohn.
  • This publication in JAMA significantly advanced the description and recognition of the gastrointestinal disease.

Purpose of the Study:

  • To explore the historical controversy surrounding the naming of Crohn's disease.
  • To discuss the contributions of Crohn, Ginzburg, and Oppenheimer to the disease's recognition.
  • To examine the evolution of understanding beyond Crohn's initial depiction.

Main Methods:

  • Historical literature review
  • Analysis of primary source documents
  • Examination of medical historical context

Main Results:

  • The naming of Crohn's disease involved a dispute among its describers.
  • Burril B. Crohn's 1932 article was pivotal but the naming was complex.
  • Phenotypic variations have been recognized beyond the original descriptions.

Conclusions:

  • The nomenclature of Crohn's disease has a complex history.
  • Understanding the disease's evolution requires acknowledging its naming controversy.
  • Further research into phenotypic variations is essential.

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