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Updated: Apr 16, 2026

Point-Of-Care Ultrasound Screening for Proximal Lower Extremity Deep Venous Thrombosis
Published on: February 10, 2023
[NHG guideline 'Deep-vein thrombosis and pulmonary embolus']
Jip de Jong1, Wim A M Lucassen, Geert-Jan Geersing
1Nederlands Huisartsen Genootschap, afd. Richtlijnontwikkeling en Wetenschap, Utrecht.
Insights
The revised Dutch guideline offers strategies for general practitioners to diagnose and manage deep-vein thrombosis (DVT) and pulmonary embolism (PE). It emphasizes using decision rules and D-dimer tests for exclusion, with specific treatment advice for DVT and superficial thrombophlebitis.
Area of Science:
- Medical Guidelines
- Cardiovascular Medicine
- General Practice
Background:
- The Nederlands Huisartsen Genootschap (NHG) has updated its guideline on deep-vein thrombosis (DVT) and pulmonary embolism (PE).
- General practitioners (GPs) require clear protocols for diagnosing and managing these conditions.
Purpose of the Study:
- To provide updated recommendations for GPs on the management of DVT, thrombophlebitis, and the exclusion of PE.
- To outline diagnostic strategies, including decision rules and D-dimer testing, for primary care settings.
Main Methods:
- The guideline incorporates clinical decision rules and the use of D-dimer testing for excluding DVT and PE.
- It details treatment approaches for DVT, including anticoagulant therapy and ultrasound follow-up.
- Recommendations for managing superficial thrombophlebitis are also included.
Main Results:
- GPs can exclude DVT or PE in select patients using a combination of a decision rule and a D-dimer test.
- The guideline advises against direct oral anticoagulants for DVT treatment within primary care.
- For isolated calf DVT, treatment options include anticoagulants or ultrasound follow-up, decided in consultation with the patient.
- Superficial thrombophlebitis management typically involves a conservative, wait-and-see approach.
Conclusions:
- The revised NHG guideline provides GPs with practical tools for the diagnosis and management of DVT and PE.
- Emphasis is placed on appropriate use of diagnostic tests and conservative management strategies where applicable.
- The guideline supports patient-centered care through shared decision-making for DVT treatment options.
Abstract:
The revised Dutch College of General Practitioners (Nederlands Huisartsen Genootschap [NHG]) guideline 'Deep-vein thrombosis and pulmonary embolus' includes recommendations for the treatment of patients with deep-vein thrombosis (DVT) and thrombophlebitis, and for the exclusion of pulmonary embolism (PE). The general practitioner (GP) can exclude the presence of DVT or PE in some patients by using a decision rule and a D-dimer test. When using D-dimer test as a point-of-care test, meticulous care is essential during the test procedure and storage of blood. The GP can treat many patients with DVT; the NHG guideline does not advise use of direct oral anticoagulants. In the case of an isolated DVT in the calf, treatment with anticoagulants or ultrasound follow-up can be chosen in consultation with the patient or on the basis of regional agreements. In the case of patients with superficial thrombophlebitis, a wait-and-see approach is usually sufficient.
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