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Updated: Apr 16, 2026

Live Imaging Characterization of Centromere Movements During Male Meiotic Prophase in Arabidopsis thaliana
Published on: October 24, 2025
TA-periodic ("601"-like) centromeric nucleosomes of A. thaliana
Reshma Nibhani1, Edward N Trifonov1
1a Genome Diversity Center, Institute of Evolution , University of Haifa , Haifa , Israel.
Abstract:
The bulk of strong nucleosomes (SNs, with visibly periodic DNA sequences) is described by consensus pattern of 5 or 6 base runs of purines alternating with similar runs of pyrimidines - RR/YY SNs. Yet, the strongest known nucleosome positioning sequence, the 601 clone of Lowary and Widom, is rather periodic repetition of TA dinucleotides following one another every 10 bases. We located "601"-like TA-periodic sequences in the genome of A. thaliana. Several families of such sequences are discovered repeating almost exclusively in centromeres. Thus, while A. thaliana SNs of RR/YY type have strong affinity to pericentromeric regions, as it has been previously found, the SNs of TA periodic type concentrate rather in centromeres.
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