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Updated: Apr 16, 2026

An Ex Vivo Chicken Primary Bursal-cell Culture Model to Study Infectious Bursal Disease Virus Pathogenesis
Published on: October 4, 2018
Immune response elicited by the oral administration of an intermediate strain of IBDV in chickens
Juan Manuel Carballeda1, Silvina Chimeno Zoth1, Evangelina Gómez1
1Instituto de Biotecnología Instituto Nacional de Tecnología Agropecuaria Buenos Aires Argentina Instituto de Biotecnología, Instituto Nacional de Tecnología Agropecuaria, Buenos Aires, Argentina. ; Consejo Nacional de Investigaciones Científicas y Técnicas Buenos Aires Argentina Consejo Nacional de Investigaciones Científicas y Técnicas, Buenos Aires, Argentina.
Abstract:
The immune response elicited by the oral inoculation of an intermediate strain of infectious bursal disease virus was studied in chickens. A strong over expression of IL-6, IL-8, IFNα and IFNγ was observed in bursa at 3 days post inoculation together with an increase in splenic NO2 release. An influx of T-lymphocytes was also detected.
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