Primary pulmonary lymphoma and cutaneous metastasis: a case report

Area of Science:

• Oncology
• Pulmonology
• Dermatology

Background:

• Diffuse large B cell lymphoma (DLBCL) is the most common non-Hodgkin's lymphoma, accounting for nearly one-third of all cases.
• Primary pulmonary lymphoma (PPL) is a rare manifestation of DLBCL involving the lungs.
• Diagnosis typically requires histopathology and immunohistochemistry.

Observation:

• A case of PPL presented with a single large lung mass on chest CT and metastatic skin lesions.
• The clinical presentation was unusual and subtle, with new onset pulmonary symptoms.
• Radiographic findings in PPL literature commonly include single or multiple nodular lesions.

Findings:

• Histopathology and immunohistochemistry confirmed PPL from transthoracic lung biopsy and skin lesion specimens.
• The patient's presentation underscores the importance of considering PPL in cases with lung mass and skin lesions.
• Radiographic review indicates nodular lesions are common presentations of PPL.

Implications:

• This case emphasizes the need to consider PPL in patients presenting with lung masses and skin lesions.
• Early and accurate diagnosis of PPL is crucial for appropriate patient management.
• Further research into the varied presentations of PPL may improve diagnostic rates.