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Related Concept Videos

lncRNA - Long Non-coding RNAs02:39

lncRNA - Long Non-coding RNAs

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In humans, more than 80% of the genome gets transcribed. However, only around 2% of the genome codes for proteins. The remaining part produces non-coding RNAs which includes ribosomal RNAs, transfer RNAs, telomerase RNAs, and regulatory RNAs, among other types. A large number of regulatory non-coding RNAs have been classified into two groups depending upon their length – small non-coding RNAs, such as microRNA, which are less than 200 nucleotides in length, and long non-coding RNA...
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RNA Pull-down Procedure to Identify RNA Targets of a Long Non-coding RNA
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Exploring the secrets of long noncoding RNAs.

Mingyang Quan1,2, Jinhui Chen3,4, Deqiang Zhang5,6

  • 1National Engineering Laboratory for Tree Breeding, College of Biological Sciences and Technology, Beijing Forestry University, Beijing 100083, China. MingyangQuan@bjfu.edu.cn.

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|March 13, 2015
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Long noncoding RNAs (lncRNAs) are crucial regulators of gene expression in plants, impacting processes like flowering time and nodulation. This review explores lncRNA functions and regulatory mechanisms, drawing parallels from animal and yeast studies.

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Area of Science:

  • Molecular Biology
  • Genetics
  • Plant Science

Background:

  • High-throughput sequencing reveals most RNAs are non-coding.
  • Long noncoding RNAs (lncRNAs) (>200 nucleotides) are key regulators.
  • lncRNA functions in transcriptional, post-transcriptional, and epigenetic gene regulation are emerging.

Purpose of the Study:

  • To review the basic mechanisms of lncRNA gene regulation.
  • To highlight the significance of plant lncRNA research.
  • To use animal and yeast lncRNA knowledge to inform plant studies.

Main Methods:

  • Literature review of existing research on lncRNAs.
  • Comparative analysis of lncRNA functions across species.
  • Focus on genome-wide identification and functional studies in plants.

Main Results:

  • lncRNAs play critical roles in gene regulation and scaffolding protein complexes.
  • Plant lncRNAs are involved in flowering time control and nodulation.
  • Emerging research indicates diverse functions for lncRNAs in plants.

Conclusions:

  • lncRNAs are vital regulatory molecules in plants, with functions extending beyond gene regulation.
  • Understanding plant lncRNAs is crucial for advancing plant biology and agriculture.
  • Further research is needed to fully elucidate lncRNA roles and mechanisms in plants.