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Factors influencing independent oral feeding in preterm infants
S M Van Nostrand1, L N Bennett1, V J Coraglio1
1Division of Neonatology, Loyola University Medical Center, Maywood, IL, USA.
Insights
Preterm infants achieve independent oral feeding around 36 weeks post-menstrual age. Factors like very early gestational age and neonatal morbidities can delay this milestone, while advances in care may accelerate it.
Area of Science:
- Neonatalogy
- Pediatric Gastroenterology
- Developmental Pediatrics
Background:
- Independent oral feeding is a critical milestone for preterm infants.
- Understanding factors influencing the timing of this skill is crucial for optimizing care.
Purpose of the Study:
- To determine the mean post-menstrual age (PMA) for achieving independent oral feeding in preterm infants.
- To investigate the impact of gestational age (GA), neonatal morbidities, gender, race, delivery route, and birth year on oral feeding attainment.
Main Methods:
- Retrospective chart review of 2700 preterm infants (born < 37 weeks GA).
- Data collected on PMA at independent oral feeding and associated clinical factors.
- Statistical analysis to identify significant predictors of feeding attainment.
Main Results:
- Mean PMA for independent oral feeding was 36 4/7 weeks.
- Infants with GA < 29 weeks had delayed feeding attainment (37 3/7 weeks).
- Necrotizing enterocolitis, bronchopulmonary dysplasia, and severe intraventricular hemorrhage significantly delayed oral feeding.
- Infants born since 2000, via vaginal delivery, and female infants achieved feeding earlier.
- Vaginal delivery and advances in neonatal care were associated with accelerated feeding.
Conclusions:
- Preterm infants typically achieve independent oral feeding by 36 4/7 weeks PMA.
- Very low GA (< 29 weeks) and major neonatal morbidities are associated with delayed feeding.
- Vaginal delivery and advancements in neonatal care may promote earlier feeding attainment.
Objective:
Determine the mean post-menstrual age when preterm infants attain independent oral feeding skills and whether gestational age, common neonatal morbidities, gender, race, delivery route, or birth year affects this reflex.
Methods:
A retrospective chart review of 2700 preterm infants, born before 37 weeks gestational age admitted to a level III NICU between January 1978 and July 2013, to determine the post-menstrual age when independent oral feedings occur.
Results:
Mean post-menstrual age at achievement of independent oral feeding was 36 + 4/7 weeks ± 14 days. Gestational age under 29 weeks correlated with delayed post-menstrual age at achievement of independent oral feeding at 37 + 3/7 weeks versus 36 + 1/7 weeks for gestational age 29-33 weeks and 36 + 3/7 weeks for late preterm infants (p < 0.0001). Preterm infants with certain morbidities experienced a delay in independent oral feeding: necrotizing enterocolitis at 38 + 6/7 weeks (p < 0.0001), bronchopulmonary dysplasia at 38 + 1/7 weeks (p < 0.0001), severe intraventricular hemorrhage at 37 + 6/7 weeks (p < 0.001). Preterm infants born before the year 2000 achieved independent oral feeding two days later than preterm infants born since the year 2000 (p < 0.0001). Preterm infants delivered vaginally achieved independent oral feeding three days sooner than infants delivered via c-section (p < 0.0001). Female infants orally fed one day sooner than male preterm infants (p = 0.0008).
Conclusions:
Preterm infants achieve independent oral feeding at 36 + 4/7 weeks. Factors negatively influencing when the preterm infant will achieve independent oral feeding include gestational age under 29 weeks and major morbidities, whereas vaginal delivery and ongoing advances in neonatal care may accelerate the transition to independent oral feeding.
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