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Hemophagocytic lymphohistiocytosis secondary to infections: a tropical experience!

P Kodan, M Chakrapani1, M Shetty

  • 1Department of Medicine, Kasturba Medical College, Manipal University, Mangalore, India.

Journal of Postgraduate Medicine
|March 14, 2015
PubMed

Hemophagocytic lymphohistiocytosis (HLH) is a potentially fatal hyper inflammatory condition, if not recognized and treated in time. A high index of suspicion can help identify the condition early. This condition can occur in the primary or secondary form. Secondary HLH or hemophagocytic syndrome (HPS) secondary to infections is an important clinical entity especially in tropical world. In this article, we share our experience with this entity and make an attempt to explore literature about ravenous macrophages which occurs secondary to infections. It is a series of six cases of HLH secondary to infectious disease in our center in a coastal city in South India over last one year with follow up.

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