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Published on: May 3, 2018
The epidemiology of blood pressure and its worldwide management
Kazem Rahimi1, Connor A Emdin2, Stephen MacMahon2
1From the Division of Cardiovascular Medicine (K.R.), Nuffield Department of Population Health (C.A.E., S.M.), The George Institute for Global Health, and Oxford Martin School (K.R., C.A.E., S.M.), University of Oxford, Oxford, United Kingdom. kazem.rahimi@georgeinstitute.ox.ac.uk.
Insights
Elevated blood pressure remains a primary global health risk. This review summarizes epidemiological evidence linking blood pressure to cardiovascular and renal diseases, highlighting trends and management strategies.
Area of Science:
- Epidemiology
- Cardiovascular Medicine
- Nephrology
Background:
- Elevated blood pressure is the leading global risk factor for disease and disability.
- Despite extensive evidence, its impact necessitates ongoing review and understanding.
Purpose of the Study:
- To review the epidemiological evidence associating blood pressure with various health conditions.
- To focus on the link between systolic and diastolic blood pressure and cardiovascular and renal disease risk.
Main Methods:
- Systematic review of epidemiological studies.
- Analysis of data on blood pressure levels, cardiovascular events, and renal disease.
- Examination of trends in blood pressure and hypertension management.
Main Results:
- Summarizes evidence on the association between blood pressure and cardiovascular and renal disease.
- Discusses the evidence for and against a J-shaped curve in blood pressure and cardiovascular risk.
- Compares the predictive power of systolic, diastolic, and pulse pressure.
Conclusions:
- Reiterates elevated blood pressure as a critical global health concern.
- Highlights the importance of understanding blood pressure associations for disease prevention.
- Underscores the need for effective hypertension management strategies worldwide.
Abstract:
Despite the vast amount of evidence on the benefits of blood pressure lowering accumulated to date, elevated blood pressure is still the leading risk factor for disease and disability worldwide. The purpose of this review is to summarize the epidemiological evidence underpinning the association between blood pressure and a range of conditions. This review focuses on the association between systolic and diastolic blood pressures and the risk of cardiovascular and renal disease. Evidence for and against the existence of a J-shaped curve association between blood pressure and cardiovascular risk, and differences in the predictive power of systolic, diastolic, and pulse pressure, are described. In addition, global and regional trends in blood pressure levels and management of hypertension are reviewed.
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