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Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma Virus (RSV) and Cancer

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Updated: Apr 16, 2026

The In ovo CAM-assay as a Xenograft Model for Sarcoma

The In ovo CAM-assay as a Xenograft Model for Sarcoma

Published on: July 17, 2013

Cervical chondrosarcoma- rare malignancy: a case report.

Shuaib Merchant¹, S M Azeem Mohiyuddin¹, Satish Rudrappa²

¹Department of ENT and Head and Neck Surgery, Sri Devraj Urs Medical College, Tamaka Kolar, 563101 India.

Indian Journal of Surgical Oncology

|March 14, 2015

Summary

This summary is machine-generated.

This case study highlights a rare vertebral bone malignancy presenting as neck swelling. Surgical resection and stabilization led to a good prognosis, emphasizing early diagnosis for deep neck masses.

Keywords:

Bone tumor Cervical spine Chondrosarcoma Supraclavicular mass

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Establishment of a Primary Culture of Patient-derived Soft Tissue Sarcoma

Establishment of a Primary Culture of Patient-derived Soft Tissue Sarcoma

Published on: April 11, 2018

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Last Updated: Apr 16, 2026

The In ovo CAM-assay as a Xenograft Model for Sarcoma

The In ovo CAM-assay as a Xenograft Model for Sarcoma

Published on: July 17, 2013

Establishment of a Primary Culture of Patient-derived Soft Tissue Sarcoma

Establishment of a Primary Culture of Patient-derived Soft Tissue Sarcoma

Published on: April 11, 2018

Area of Science:

Orthopedic Oncology
Neurosurgery
Radiology

Background:

Bone malignancies in the cervical spine are rare.
Deep-seated neck swellings often present diagnostic challenges.

Observation:

A 30-year-old male presented with a year-long left supraclavicular neck swelling and six months of left upper limb numbness.
MRI revealed a 7.4 x 4.6 cm expansile lesion involving the C5-C7 transverse processes.

Findings:

A dual surgical approach (anterior cervical and posterior spinal) was necessary due to the tumor's deep location near the phrenic nerve and brachial plexus.
En-bloc tumor resection with iliac crest grafting and cervical spine stabilization was performed.

Implications:

Vertebral tumors should be considered in the differential diagnosis of deep, hard neck swellings.
Early diagnosis and complete resection of even low-grade vertebral malignancies can lead to favorable outcomes.