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IgG4-Related Nasal Pseudotumor
L K Døsen1, P Jebsen2, B Dingsør3
1Department of Otorhinolaryngology, Lovisenberg Diakonale Hospital, 0440 Oslo, Norway.
Abstract:
IgG4-related disease is recognized as one form of autoimmune pancreatitis. During the last ten years, it has also been described in several other organs. We present two patients with lesions showing a histological picture of fibrosis and lymphoplasmacytic infiltrations with abundant IgG4 positive plasma cells at hitherto unreported symmetrical nasal locations. The symmetrical complex consisted of one central lesion in the anterior nasal septum and the two others in each of the lateral nasal walls. The lesions extended from the anterior part of the inferior concha into the vestibulum and caused severe nasal obstruction.
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