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Human milk pasteurization: benefits and risks
Deborah L O'Connor1, Julia B Ewaschuk, Sharon Unger
1aDepartment of Nutritional Sciences bDepartment of Paediatrics and Neonatology, University of Toronto cPhysiology and Experimental Medicine Program, The Hospital for Sick Children, Toronto dDepartment of Agricultural, Food and Nutritional Sciences, University of Alberta, Edmonton eDepartment of Paediatrics, Mount Sinai Hospital, Toronto, Ontario, Canada.
Insights
Nutrient-enriched human milk, often pasteurized donor milk, is optimal for preterm, very low birth weight infants (VLBW). Pasteurization ensures safety while largely preserving nutritional and immunological benefits for improved VLBW infant outcomes.
Area of Science:
- Neonatal Nutrition
- Human Milk Science
- Infant Health
Background:
- Optimal nutrition for preterm, very low birth weight (VLBW) infants (<1500g) involves nutrient-enriched human milk.
- Pasteurized donor milk is increasingly utilized in neonatal intensive care units (NICUs) in North America.
- Growing availability of donor milk necessitates a review of its safety and efficacy.
Purpose of the Study:
- To review recent evidence on the risks and benefits of human milk pasteurization.
- To summarize outcomes associated with providing pasteurized donor milk to VLBW preterm infants.
Main Methods:
- Review of recent scientific literature.
- Analysis of studies on human milk collection, storage, and pasteurization.
- Evaluation of impacts on nutritional, immunological, and bacteriostatic properties.
Main Results:
- Pasteurization partially reduces human milk bioactivity but significantly mitigates contamination risks.
- Ongoing research explores novel pasteurization methods to better preserve milk's beneficial properties.
- Studies indicate that pasteurized donor milk remains a valuable nutritional source for VLBW infants.
Conclusions:
- Provision of human milk, including pasteurized donor milk, is linked to enhanced outcomes in preterm VLBW infants.
- Pasteurization is a critical step in ensuring the safety of donor human milk for vulnerable infants.
Purpose Of Review:
Recent findings substantiate that the optimal method of nourishing preterm, very low birth weight infants (VLBW, born <1500 g) is through appropriately nutrient-enriched human milk, which is frequently provided as pasteurized donor milk. The availability of donor milk for VLBW infants during initial hospitalization continues to increase with the launch of new milk banks in North America. The majority of North American neonatal ICUs now have written policies governing the provision of donor milk. The purpose of this review is to summarize recent evidence regarding the risks and benefits of pasteurization of human milk and outcomes associated with its provision to VLBW preterm infants.
Recent Findings:
Studies investigating the impact of collection, storage and pasteurization on the bacteriostatic, immunologic and nutritional aspects of human milk continue to be published, generally revealing a partial, but not complete reduction in bioactivity. Risk of contamination of pasteurized donor human milk with pathogenic agents is mitigated through pasteurization. New pasteurization methods aiming to maintain the safety of pooled human milk while better preserving bioactivity are under investigation.
Summary:
Provision of a human milk-derived diet to preterm VLBW infants is associated with improved outcomes.
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