Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Fungal Phylum Microsporidia01:28

Fungal Phylum Microsporidia

759
Microsporidia are a group of obligate intracellular fungi that were initially classified as protists but were later reclassified based on phylogenetic, molecular, and structural evidence linking them to the Chytridiomycota. These unicellular, non-motile organisms are highly specialized parasites that infect a wide range of animal hosts, including humans. They have evolved extensive genomic and metabolic reductions, making them highly dependent on their hosts for survival.Morphology and Genomic...
759

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Prevalence and molecular identification of protozoan parasites in cancer patients in Jordan.

Journal of infection in developing countries·2026
Same author

Low Vitamin D and C Levels are Associated with Increased Disease Activity in Jordanian RA and SLE Patients: A Case-Control Study

Endocrine, metabolic & immune disorders drug targets·2026
Same author

Molecular analysis of Cryptosporidium species in Western Australian human populations (2023-2025), and the emergence of rare C. hominis IeA11G3T3 subtype.

Parasitology international·2025
Same author

The status of strongyloidiasis in the Mediterranean countries.

Journal of infection in developing countries·2025
Same author

<i>Cryptosporidium</i> in cattle: Assessing the zoonotic risk.

Current research in parasitology & vector-borne diseases·2025
Same author

Microphysiological gut-on-chip enables extended <i>in vitro</i> development of <i>Cryptosporidium hominis</i>.

Frontiers in cellular and infection microbiology·2025

Related Experiment Video

Updated: Apr 16, 2026

Studying Cryptosporidium Infection in 3D Tissue-derived Human Organoid Culture Systems by Microinjection
05:31

Studying Cryptosporidium Infection in 3D Tissue-derived Human Organoid Culture Systems by Microinjection

Published on: September 14, 2019

10.4K

New developments in Cryptosporidium research.

Una Ryan1, Nawal Hijjawi2

  • 1School of Veterinary and Life Sciences, Vector- and Water-Borne Pathogen Research Group, Murdoch University, Murdoch, Western Australia 6150, Australia.

International Journal for Parasitology
|March 15, 2015
PubMed
Summary

Cryptosporidium, a leading cause of childhood diarrhea, is closely related to gregarine parasites. Understanding this link and its biochemistry offers new pathways for developing treatments and vaccines against this significant enteric pathogen.

Keywords:
Cell cultureCryptosporidiumDrug developmentGenomicsTaxonomyVaccines

More Related Videos

A Modified EPA Method 1623 that Uses Tangential Flow Hollow-fiber Ultrafiltration and Heat Dissociation Steps to Detect Waterborne Cryptosporidium and Giardia spp.
12:11

A Modified EPA Method 1623 that Uses Tangential Flow Hollow-fiber Ultrafiltration and Heat Dissociation Steps to Detect Waterborne Cryptosporidium and Giardia spp.

Published on: July 9, 2012

21.2K
Complementary Use of Microscopic Techniques and Fluorescence Reading in Studying Cryptococcus-Amoeba Interactions
10:56

Complementary Use of Microscopic Techniques and Fluorescence Reading in Studying Cryptococcus-Amoeba Interactions

Published on: June 22, 2019

6.8K

Related Experiment Videos

Last Updated: Apr 16, 2026

Studying Cryptosporidium Infection in 3D Tissue-derived Human Organoid Culture Systems by Microinjection
05:31

Studying Cryptosporidium Infection in 3D Tissue-derived Human Organoid Culture Systems by Microinjection

Published on: September 14, 2019

10.4K
A Modified EPA Method 1623 that Uses Tangential Flow Hollow-fiber Ultrafiltration and Heat Dissociation Steps to Detect Waterborne Cryptosporidium and Giardia spp.
12:11

A Modified EPA Method 1623 that Uses Tangential Flow Hollow-fiber Ultrafiltration and Heat Dissociation Steps to Detect Waterborne Cryptosporidium and Giardia spp.

Published on: July 9, 2012

21.2K
Complementary Use of Microscopic Techniques and Fluorescence Reading in Studying Cryptococcus-Amoeba Interactions
10:56

Complementary Use of Microscopic Techniques and Fluorescence Reading in Studying Cryptococcus-Amoeba Interactions

Published on: June 22, 2019

6.8K

Area of Science:

  • Parasitology
  • Molecular Biology
  • Infectious Diseases

Background:

  • Cryptosporidium is a major enteric parasite causing significant childhood diarrhea and mortality globally.
  • Cryptosporidium hominis and Cryptosporidium parvum are the primary species responsible for human infections.
  • Existing treatments and vaccines are limited due to laboratory challenges and incomplete understanding of the parasite.

Purpose of the Study:

  • To investigate the phylogenetic relationship of Cryptosporidium with other parasites.
  • To explore novel therapeutic and control strategies for Cryptosporidium infections.
  • To identify new drug targets through advanced molecular and biochemical analyses.

Main Methods:

  • Phylogenetic analysis based on molecular and biological studies.
  • Identification of gregarine-like gamont stages.
  • Whole genome sequencing and metabolomics.

Main Results:

  • Cryptosporidium shows a closer evolutionary relationship to gregarine parasites than to coccidians.
  • Evidence supports gregarine-like gamont stages and extracellular life cycle completion.
  • Genomic and metabolomic data have revealed crucial biochemical requirements and potential drug targets.

Conclusions:

  • The gregarine-like nature of Cryptosporidium opens new research avenues for pathogenesis and control.
  • Advanced techniques like whole genome sequencing are crucial for understanding parasite biochemistry.
  • Increased funding is essential to overcome technical hurdles and develop effective treatments and vaccines against Cryptosporidium.