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Updated: Apr 16, 2026
08:49
A 3D Organotypic Melanoma Spheroid Skin Model
Published on: May 18, 2018
16.8K
Pathology of melanoma
1Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104, USA.
Surgical Oncology Clinics of North America
|March 15, 2015
Summary
Melanoma diagnosis and management rely on surgical pathology. Future treatments may involve genomic factors, but surgery and histopathology remain essential for melanoma care.
Area of Science:
- Oncology
- Surgical Pathology
- Genomics
Background:
- Melanoma diagnosis and management present challenges in clinicopathologic communication.
- Histopathologic diagnosis and surgical therapy are currently central to melanoma patient care.
Purpose of the Study:
- To discuss the pathology of melanoma in the context of surgical diagnosis and management.
- To highlight potential pitfalls in clinicopathologic communication.
- To explore the future role of genomic factors in melanoma treatment.
Main Methods:
- Review of melanoma pathology.
- Analysis of clinicopathologic communication in surgical diagnosis.
- Discussion of current and future therapeutic strategies.
Main Results:
- Clinicopathologic communication pitfalls can complicate melanoma management.
- Targeted therapies based on genomic factors show promise but have limitations.
- Histopathologic diagnosis and surgical intervention remain critical.
Conclusions:
- Effective communication between pathologists and surgeons is vital for optimal melanoma management.
- Genomic characterization of tumors offers a future paradigm for targeted therapy.
- Despite advancements, histopathology and surgery will continue as foundational elements in melanoma treatment.
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