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Skin Cancer

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
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Single-port Non-liposuction Endoscopic Axillary Lymph Node Dissection in Breast Cancer Surgery

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Lymph node dissection for stage III melanoma.

Maggie L Diller¹, Benjamin M Martin¹, Keith A Delman¹

¹Division of Surgical Oncology, Department of Surgery, Winship Cancer Institute-Emory University, 1365 Clifton Road, Atlanta, GA 30322, USA.

Surgical Oncology Clinics of North America

|March 15, 2015

Summary

This summary is machine-generated.

Melanoma spread to lymph nodes worsens prognosis. Sentinel lymph node-positive or palpable nodal disease requires lymphadenectomy, with potential for adjunct therapies and improved surgical techniques.

Keywords:

Locoregional spread Lymphadenectomy Stage III melanoma Videoscopic inguinal lymphadenectomy

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Area of Science:

Oncology
Surgical Oncology
Dermatology

Background:

Locoregional spread of melanoma to lymph nodes is a critical prognostic indicator.
Nodal metastasis significantly impacts patient outcomes in melanoma.
Sentinel lymph node status and palpable nodal disease guide treatment decisions.

Purpose of the Study:

To review the management and technical aspects of surgical care for regional melanoma metastases.
To discuss the role of lymphadenectomy in patients with nodal disease.
To explore adjunct therapies and potential improvements in surgical techniques.

Main Methods:

Review of current literature on the surgical management of regional melanoma spread.
Discussion of lymphadenectomy procedures for sentinel lymph node-positive and palpable nodal disease.
Analysis of adjunct therapies including immunotherapy, targeted therapy, and radiation.

Main Results:

Lymphadenectomy is indicated for sentinel lymph node-positive or palpable nodal disease.
Adjunct therapies can supplement lymphadenectomy in specific patient groups.
Surgical morbidity associated with lymphadenectomy presents opportunities for technique refinement.

Conclusions:

Effective management of regional melanoma spread involves lymphadenectomy and consideration of adjunct therapies.
Minimally invasive techniques and improved patient selection may reduce surgical morbidity.
Optimizing surgical care is crucial for improving outcomes in patients with nodal melanoma metastasis.