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Published on: August 16, 2018
Trinorcassane and cassane diterpenoids from the seeds of Caesalpinia minax
Yong Zheng1, Shu-Wei Zhang1, Li-Jiang Xuan1
1State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 501 Haike Road, Zhangjiang Hi-Tech Park, Shanghai 201203, PR China.
Abstract:
An unprecedented trinorcassane diterpenoid and a cassane furanoditerpenoid were isolated from the seeds of Caesalpinia minax. It is the first example of dicylic cassane-type trinorditerpenoid, which is different from reported 16- or 17-norcassane diterpenoids. The structure of the compounds was elucidated on the basis of 1D and 2D NMR analysis. Biosynthesis pathways are postulated, and this pathway was supported by semi-synthesis.
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