Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Pathophysiologic principles of modern liver surgery].

S Bengmark1

  • 1Chirurgische Universitätsklinik, Universität Lund, Schweden.

Langenbecks Archiv Fur Chirurgie. Supplement II, Verhandlungen Der Deutschen Gesellschaft Fur Chirurgie. Deutsche Gesellschaft Fur Chirurgie. Kongress
|January 1, 1989
PubMed
Summary

Successful liver surgery relies on liver regeneration. Fibronectin, a key factor, increases after liver removal and may be crucial for restoring liver function, especially complex processes like bile salt production.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Liver Surgery.

Progress in surgery·2017
Same author

Effect of pre- and probiotics on liver regeneration after resection: a randomised, double-blind pilot study.

Beneficial microbes·2012
Same author

[Bio-ecological control of chronic liver disease and encephalopathy].

Minerva medica·2011
Same author

The effect of testosterone in partially hepatectomized female rats.

Scandinavian journal of gastroenterology·2010
Same author

Plant-derived health: the effects of turmeric and curcuminoids.

Nutricion hospitalaria·2009
Same author

[Advanced glycation and lipoxidation end-products amplify inflammation. The role of a healthy diet].

Minerva medica·2008

Area of Science:

  • Hepatology
  • Molecular Biology
  • Regenerative Medicine

Context:

  • Liver regeneration is critical for recovery after surgical resection (hepatectomy).
  • Current understanding primarily derives from rat models, highlighting a lag in functional recovery compared to morphological regeneration.
  • Sophisticated liver functions, including bile salt metabolism, normalize slowly post-hepatectomy.

Purpose:

  • To review the multifaceted factors influencing hepatic regeneration.
  • To highlight fibronectin as a key factor of current research interest in liver regeneration.
  • To explore the potential role of fibronectin in accelerating functional liver recovery.

Summary:

  • Liver regeneration is essential for successful surgical outcomes.
  • While structural liver regeneration is rapid, functional recovery, particularly bile salt production and conjugation, is delayed.

Related Experiment Videos

  • Increased plasma fibronectin secretion post-hepatectomy is observed, suggesting its significant role in hepatic regeneration.

    • Impact:

    • Identifies fibronectin as a potentially critical factor for enhancing liver regeneration.
    • Provides insights into the complex mechanisms of liver functional recovery.
    • Informs future research directions for therapeutic strategies targeting liver regeneration.