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Updated: Apr 16, 2026
Nanosensors to Detect Protease Activity In Vivo for Noninvasive Diagnostics
Published on: July 16, 2018
A continuous-flow mass biosensor for the real-time dynamic analysis of protease inhibition
Yanyan Huang1, Qundan Zhang, Guoquan Liu
1Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Analytical Chemistry for Living Biosystems, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China. zhaorui@iccas.ac.cn.
Abstract:
A flow injection analysis-quartz crystal microbalance (FIA-QCM) biosensor was developed for probing the dynamic interactions during protease inhibition. Being sensitive to conformation features of different proteases, this continuous-flow sensor has potential for structural-functional analysis and inhibitor selection.
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