[Comparative study between pirprofen (Rengasil) and piritramid (Dipidolor) for postoperative pain in maxillofacial...

In this clinical single-blind trial, the potential analgesic effect of pirprofen (Rengasil) was compared to the analgesic effect of piritramide (Dipidolor). The two compounds were tested intramuscularly in patients submitted to maxillofacial surgery. Pirprofen and piritramide seem to have an equivalent analgesic effect but pirprofen (Rengasil) seems to act a little faster and to be better tolerated than piritramide. Therefore, pirprofen may be utilized with success to treat postoperative pain in patients who undergo maxillofacial surgery: its advantage is avoiding secondary effects of the morphinomimetic compounds.