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Cognitive behavioural interventions for depression in chronic neurological conditions: a systematic review

Bruce A Fernie1, Josianne Kollmann2, Richard G Brown3

  • 1King's College London, Institute of Psychiatry, Department of Psychology, London, UK; CASCAID, South London & Maudsley NHS Foundation Trust, London, UK.

Journal of Psychosomatic Research
|March 18, 2015
PubMed

Insights

Cognitive Behavioral Therapy (CBT) shows promise for treating depression in chronic neurological conditions (CNCs). However, adaptations to CBT protocols and outcome measures are needed for this population.

Area of Science:

  • Neurology
  • Psychiatry
  • Clinical Psychology

Background:

  • Chronic neurological conditions (CNCs) affect over a million people in the UK.
  • Depression and anxiety are highly prevalent in individuals with CNCs, worsening prognosis and increasing healthcare costs.
  • Cognitive Behavioral Therapy (CBT) is a recommended treatment for depression, but its application in CNCs faces challenges due to disease characteristics.

Purpose of the Study:

  • To assess the clinical effectiveness of cognitive and behavioral interventions for depressive symptoms in individuals with non-acquired, medically explained CNCs.

Main Methods:

  • Systematic literature searches were conducted in The Cochrane Controlled Trials Register, PubMed, and PsychInfo.

Main Results:

  • Evidence suggests CBT is effective for treating depression comorbid with CNCs.
  • However, comparisons between CBT and active therapy control groups showed unstable between-group differences.

Conclusions:

  • CBT holds potential for treating depression in individuals with CNCs.
  • Treatment protocols and outcome measures require adaptation for this specific population.
  • Future research should control for non-specific therapy effects and incorporate blinding.
Abstract

Keywords:
Alzheimer's diseaseCBTDepressionEpilepsyMultiple sclerosisParkinson's disease

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