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Expression and localization of aromatase during fetal mouse testis development

Caroline Borday1, Jorge Merlet1, Chrystèle Racine1

  • 1Laboratory of Development of the Gonads, Unit of Stem Cells and Radiation, Univ. Paris Diderot, Sorbonne Paris Cité, BP 6, 92265 Fontenay-aux-Roses, France ; CEA, DSV, iRCM, SCSR, LDG, 92265 Fontenay-aux-Roses, France ; Unit of Stem Cells and Radiation, LDG / SCSR / iRCM / DSV, INSERM, Centre CEA, BP6, Unité 967, F-92265 Fontenay aux Roses, France.

Basic and Clinical Andrology
|March 18, 2015
PubMed
Summary

Aromatase, crucial for hormone balance, is expressed early in mouse fetal testis development, including in germ cells. This finding suggests a species-specific role in endocrine disruption susceptibility.

Keywords:
AromataseCellules de LeydigCyp19a1DevelopmentDéveloppementEndocrine disruptorsFetusGonocytesLeydig cellsMousePerturbateurs endocriniensSourisTestis

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