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Updated: Apr 16, 2026
Hand-held Clinical Photoacoustic Imaging System for Real-time Non-invasive Small Animal Imaging
Published on: October 16, 2017
Photoacoustic imaging of acupuncture effect in small animals
Tingting Li1, Xueliang Xu2, Bingzhang Chen3
1School of Physical Electronics, University of Electronic Science and Technology of China, Chengdu, Sichuan, China ; These authors contributed equally to this work.
Abstract:
Acupuncture has been a powerful clinical tool for treating chronic diseases. However, there is currently no appropriate method to clarify the therapeutic effect of acupuncture. Here, we use photoacoustic tomography (PAT) to study the effect of acupuncture on mouse brain blood vessels. Ten healthy mice were stimulated with acupuncture needles on two acupoints. PAT images were obtained before and after acupuncture. We report that stimulation of certain acupoints resulted in changes in hemodynamics/blood flow at these points. The results demonstrate that PAT can non-invasively detect blood flow changes in mouse brain under acupuncture. This pilot study shows the potential of PAT as a visualization tool for illuminating the mechanism of acupuncture and promoting its clinical applications.
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