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Updated: Apr 16, 2026
Sectioning Mammary Gland Whole Mounts for Lesion Identification
Published on: July 24, 2017
Scleromyxedema with histology resembling granuloma annulare
Samyukta Mullangi, Scott R Granter, Jacob P Laubach
1Brigham and Women's Hospital.
Abstract:
Scleromyxedema is a generalized and progressive fibromucinous disorder associated with substantial cutaneous and systemic morbidity. The diagnosis is often challenging, as is management. We present here a patient with scleromyxedema with atypical, granuloma annulare-like histology, which contributed to delayed diagnosis and management, including a delayed workup for multiple myeloma. Ultimately, the patient did well with appropriate therapy, but his presentation illustrates the importance of more widespread familiarity among dermatologists and dermatopathologists with this variant of scleromyxedema.
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