Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Synthesis and Regulation of Thyroid Hormones01:20

Synthesis and Regulation of Thyroid Hormones

8.4K
Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
8.4K
Functions of Thyroid Hormones01:18

Functions of Thyroid Hormones

6.0K
The thyroid hormone (TH) plays a pivotal role in the intricate orchestration of physiological processes, exerting profound effects on development, metabolism, and homeostasis throughout different life stages.
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
6.0K
The Thyroid Gland01:23

The Thyroid Gland

8.1K
The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
8.1K
Inborn Errors of Metabolism01:20

Inborn Errors of Metabolism

957
Phenylketonuria (PKU) is a protein metabolism disorder characterized by high blood levels of the amino acid phenylalanine. This results from a mutation in the gene responsible for phenylalanine hydroxylase, an enzyme that converts phenylalanine into tyrosine. When this enzyme is deficient, phenylalanine builds up in the blood, leading to symptoms such as vomiting, rashes, seizures, growth deficiency, and severe mental retardation. An early diagnosis and a diet restricting phenylalanine intake...
957
Adrenal Gland Disorders01:27

Adrenal Gland Disorders

3.6K
Adrenal gland disorders manifest when the production of adrenal hormones deviates from the norm, resulting in either excessive or insufficient concentrations.
Adrenal insufficiency, characterized by insufficient cortisol and aldosterone production, leads to conditions like Addison's disease. This disorder, affecting the adrenal cortex, exhibits symptoms such as skin bronzing, dehydration, low blood pressure, fatigue, and weight loss. Congenital adrenal hyperplasia, a genetic ailment causing...
3.6K
Hypoglycemia and Glucagon01:15

Hypoglycemia and Glucagon

1.1K
Without prolonged fasting, healthy individuals maintain blood glucose levels above 3.5 mM due to a well-adapted neuroendocrine counterregulatory system that effectively prevents acute hypoglycemia, a potentially life-threatening condition. The primary clinical scenarios for hypoglycemia encompass diabetes treatment, inappropriate production of endogenous insulin or insulin-like substances by tumors, and the use of glucose-lowering agents in non-diabetic individuals. Notably, hypoglycemia in the...
1.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Human Fecal Microbiota Transplantation Reduces the Susceptibility to Dextran Sulfate Sodium-Induced Germ-Free Mouse Colitis.

Frontiers in immunologyยท2022
Same author

Correlation between the regulation of intestinal bacteriophages by green tea polyphenols and the flora diversity in SPF mice.

Food & functionยท2022
Same author

Oral Administration of Bacterial <i>ฮฒ</i> Cell Expansion Factor A (BefA) Alleviates Diabetes in Mice with Type 1 and Type 2 Diabetes.

Oxidative medicine and cellular longevityยท2022
Same author

Neonatal Adverse Events' Trigger Tool Setup With Random Forest.

Journal of patient safetyยท2022
Same author

Diffusion MRI super-resolution reconstruction via sub-pixel convolution generative adversarial network.

Magnetic resonance imagingยท2022
Same author

A Combined-Radiomics Approach of CT Images to Predict Response to Anti-PD-1 Immunotherapy in NSCLC: A Retrospective Multicenter Study.

Frontiers in oncologyยท2022

Related Experiment Video

Updated: Feb 27, 2026

Minimal Invasive Resection of Large Retrosternal Thyroid Goiter
04:09

Minimal Invasive Resection of Large Retrosternal Thyroid Goiter

Published on: September 20, 2024

1.0K

Neonatal thyroid storm accompanied with severe anaemia.

Lu-Ying Cao, Hong Wei, Zheng-Li Wang

    Journal of Pediatric Endocrinology & Metabolism : JPEM
    |March 18, 2015
    PubMed
    Summary

    Neonatal thyroid storm is a rare but serious condition in infants. This case highlights the challenges in diagnosing and managing this critical illness, even after initial treatment.

    Area of Science:

    • Neonatology
    • Endocrinology
    • Pediatrics

    Background:

    • Neonatal thyroid storm is a rare and severe manifestation of hyperthyroidism in newborns.
    • Established diagnostic criteria and management protocols for neonatal thyroid storm are lacking.
    • Maternal Graves' disease is a known cause of neonatal hyperthyroidism.

    Observation:

    • A preterm infant with neonatal hyperthyroidism due to maternal Graves' disease was initially treated and discharged.
    • The infant was subsequently rehospitalised due to the development of neonatal thyroid storm.
    • This case underscores the potential for recurrence or delayed presentation of severe thyrotoxicosis.

    Findings:

    • The case report details the diagnostic process for a neonate experiencing thyroid storm.

    More Related Videos

    Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model
    04:39

    Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model

    Published on: March 17, 2023

    2.6K
    An Orthotopic Mouse Model of Anaplastic Thyroid Carcinoma
    07:01

    An Orthotopic Mouse Model of Anaplastic Thyroid Carcinoma

    Published on: April 17, 2013

    21.7K

    Related Experiment Videos

    Last Updated: Feb 27, 2026

    Minimal Invasive Resection of Large Retrosternal Thyroid Goiter
    04:09

    Minimal Invasive Resection of Large Retrosternal Thyroid Goiter

    Published on: September 20, 2024

    1.0K
    Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model
    04:39

    Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model

    Published on: March 17, 2023

    2.6K
    An Orthotopic Mouse Model of Anaplastic Thyroid Carcinoma
    07:01

    An Orthotopic Mouse Model of Anaplastic Thyroid Carcinoma

    Published on: April 17, 2013

    21.7K
  • It emphasizes the critical need for vigilant monitoring and timely intervention in affected infants.
  • The management challenges associated with this rare condition are highlighted.

    • Implications:

    • Improved diagnostic criteria and standardized management guidelines for neonatal thyroid storm are needed.
    • Early recognition and aggressive treatment are crucial for improving outcomes in affected neonates.
    • Further research into the pathophysiology and long-term effects of neonatal thyroid storm is warranted.