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Updated: Apr 16, 2026

Isolating Central Nervous System Tissues and Associated Meninges for the Downstream Analysis of Immune cells
Published on: May 19, 2020
[Infectious-inflammatory complications of cerebral insulitis]
Abstract:
Pneumonia and urinary tract infections develop in roughly 1/3 of the survivors of cerebral stroke. Post-stroke pneumonia results from aspiration and uroinfection from neurogenic disturbances of urination and bladder catheterization. Post-stroke immune deficiency increases the risk of infectious and inflammatory complications. These conditions are treated in accordance with the general principles of management of these diseases. Prophylaxis of pneumonia is reduced to the principle of "nothing orally" before the swallowing capacity is tested, early mobilization, and oral cavity hygiene. Studies on the role of prophylactic antibiotic therapy and ACE inhibitors in the prevention of post-stroke pneumonia are currently underway. Bladder catheterization under strict indications and the use ofcatheters coated with antibacterial agents or condom urine bags in men are likely to reduce the risk of uroinfection. Infectious and inflammatory complications impair the outcome of stroke. Their prophylaxis and adequate treatment are prerequisites of successful recovery after stroke.
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