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Real-Time Cardiac Mapping with a Noninvasive Imageless Electrocardiographic Imaging System

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Analysis of cardiac fibrillation using phase mapping.

Richard H Clayton¹, Martyn P Nash²

¹Insigneo Institute for in-silico medicine and Department of Computer Science, University of Sheffield, Regent Court, 211 Portobello Street, Sheffield S1 4DP, UK.

Cardiac Electrophysiology Clinics

|March 19, 2015

Summary

Phase analysis visualizes myocardial electrical activity during fibrillation. This method helps identify reentrant waves and track wavefronts, potentially guiding atrial ablation procedures.

Keywords:

Atrial fibrillation Cardiac arrhythmia Mapping Phase analysis Reentry Ventricular fibrillation

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Area of Science:

Cardiology
Biophysics
Medical Imaging

Background:

Myocardial electrical activation during fibrillation is complex and dynamic.
Phase analysis offers a method to represent the electrical activation-recovery process.
Phase singularities are key markers in identifying reentrant wave circuits.

Purpose of the Study:

To explain the fundamental principles of phase analysis in cardiac electrophysiology.
To review recent advancements in electrogram preprocessing for reliable phase estimation.
To highlight the potential of phase analysis in guiding atrial ablation.

Main Methods:

Utilizing phase analysis to represent the electrical activation-recovery process as an angle.
Identifying phase singularities where lines of equal phase converge.
Automating the detection and tracking of reentrant wavefronts.
Implementing advanced electrogram preprocessing techniques.

Main Results:

Phase analysis successfully identifies reentrant wave circuits by locating phase singularities.
Automated tracking of reentrant wavefronts is achievable through phase analysis.
Recent preprocessing developments enhance the reliability of phase estimation from electrograms.

Conclusions:

Phase analysis is a valuable tool for understanding complex cardiac electrical activity.
Reliable phase estimation is crucial for the clinical application of this technique.
Phase analysis holds significant promise for guiding catheter ablation in the human heart.