Related Experiment Video
Updated: Apr 16, 2026

Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform
Published on: April 12, 2021
The development of the ProMAS: a Probabilistic Medication Adherence Scale
Mieke Kleppe1, Joyca Lacroix2, Jaap Ham3
1Human Technology Interaction, Eindhoven University of Technology, Eindhoven, the Netherlands ; Behavior, Cognition and Perception, Philips Research, Eindhoven, the Netherlands.
This study introduces the Patient Medication Adherence Scale (ProMAS), a new self-report tool. ProMAS offers a wider range of adherence behaviors, reducing skewness and improving accuracy in measuring medication adherence.
Area of Science:
- Health outcomes research
- Psychometrics
- Geriatric medicine
Background:
- Current self-report medication adherence measures often yield skewed data with limited variance, contradicting objective findings.
- A key limitation is the restricted range of behaviors assessed, leading to a ceiling effect in self-reported adherence.
Purpose of the Study:
- To introduce and validate a new self-reported medication adherence scale, the Patient Medication Adherence Scale (ProMAS).
- To address the limitations of existing measures by covering a broader spectrum of adherence behaviors using the Rasch model.
Main Methods:
- Development of the ProMAS using the Rasch model approach.
- Validation of the ProMAS with 370 elderly individuals undergoing medication for chronic conditions.
Main Results:
- The ProMAS demonstrated sufficient fit to the Rasch model, providing reliable adherence scores.
- ProMAS covered a wider range of adherence behaviors than the Medication Adherence Report Scale (MARS).
- ProMAS resulted in less skewness and greater variance in adherence scores compared to MARS.
Conclusions:
- The ProMAS is a more effective tool for measuring medication adherence in elderly populations with chronic conditions.
- ProMAS offers improved discrimination between individuals with varying adherence rates compared to the MARS.
More Related Videos
Related Concept Videos
Dosage Regimens: Designs and Approaches
Pharmacovigilance
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
Drug Therapy
Antianxiety Medications
Drug Dosing: Geriatric Patients
Dosage Regimens: Partial Pharmacokinetic Parameters
Dosage Regimen Designs: Nomograms and Tabulations

