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An observational study on infective endocarditis: a single center experience

Seyed Mohammad Javad Hosseini1, Ramezan Bakhshian2, Maryam Moshkani Farahani2

  • 1Molecular Biology Research Center, Baqiyatallah University of Medical Sciences, Tehran, IR Iran.

Research in Cardiovascular Medicine
|March 19, 2015
PubMed
Abstract

Insights

Infective endocarditis (IE) is a serious condition requiring prompt attention. Echocardiography, particularly TEE, is crucial for detecting vegetations and complications, aiding in timely treatment and improving patient outcomes.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Medical Imaging

Background:

  • Infective endocarditis (IE) originates from microbial colonization of heart endothelium.
  • The characteristic lesion, vegetation, comprises platelets, fibrin, microorganisms, and inflammatory cells.

Purpose of the Study:

  • To evaluate patients with infective endocarditis (IE).
  • To analyze echocardiographic data, comparing transthoracic echocardiography (TTE) and transesophageal echocardiography (TEE).
  • To assess the impact of IE on native and prosthetic valves.

Main Methods:

  • Retrospective study of 35 IE patients (2007-2010).
  • Standardized echocardiography and laboratory tests performed for all patients.
  • Statistical analysis using SPSS 16.

Main Results:

  • Fever (80%) and chills (65.7%) were predominant symptoms.
  • Mitral valve (54.2%) and aortic valve (48.5%) were most frequently affected.
  • Transesophageal echocardiography (TEE) demonstrated 100% specificity and 88.6% sensitivity; 17.1% mortality and 17.1% surgical intervention rate.

Conclusions:

  • Infective endocarditis (IE) carries a high mortality rate if untreated.
  • Echocardiography is vital for identifying vegetations and complications like abscesses and paravalvular leaks.
  • Prompt diagnosis and management are essential for improving patient outcomes.
Keywords:
Infective EndocarditisTransesophageal EchocardiographyTransthoracic Echocardiography

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