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Updated: Apr 16, 2026

Automated Measurement of Pulmonary Emphysema and Small Airway Remodeling in Cigarette Smoke-exposed Mice
Published on: January 16, 2015
Cigarette smoke resets the Alarmin IL-33 in COPD
1Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8TA, UK; School of Biology and Basic Medical Sciences, Soochow University, Suzhou 215006, China.
Abstract:
Cigarette smoke and infection are the major drivers of chronic obstructive pulmonary disease. In this issue of Immunity, Kearley et al. (2015) demonstrate that smoke exposure alters the lung microenvironment leading to an interleukin-33-dependent proinflammatory disease exacerbation.
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