Sweet's syndrome and pyoderma gangrenosum associated with ulcerative colitis

Area of Science:

• Dermatology
• Gastroenterology
• Internal Medicine

Background:

• Ulcerative colitis (UC) is a chronic inflammatory bowel disease.
• Pyoderma gangrenosum (PG) and Sweet's syndrome (SS) are rare neutrophilic dermatoses.
• These conditions can be associated with systemic diseases, including inflammatory bowel disease.

Observation:

• A case of a young woman with ulcerative colitis is presented.
• The patient developed pyoderma gangrenosum during the active phase of her ulcerative colitis.
• Three months after undergoing panproctocolectomy, she developed Sweet's syndrome.

Findings:

• The patient exhibited two distinct neutrophilic dermatoses.
• Pyoderma gangrenosum occurred during active ulcerative colitis.
• Sweet's syndrome manifested three months after surgical intervention for ulcerative colitis.

Implications:

• This case underscores the complex relationship between ulcerative colitis and specific dermatological conditions.
• It highlights the potential for diverse cutaneous manifestations in patients with inflammatory bowel disease.
• Understanding these associations is crucial for comprehensive patient management and treatment strategies.