Electrospun collagen and its applications in regenerative medicine

In recent years, electrospinning has increased in popularity as a processing technique for obtaining nanometer-to-micron diameter polymer fibers collected to form a nonwoven scaffold. It possesses the ability to process collagen into nanofibrous scaffolds which have been used for a number of applications, such as artificial vascular grafts and for wound repair. This paper offers a review of some of the basic yet essential aspects of producing nanofibrous scaffolds of collagen by electrospinning. A primer to collagen structure, cross-linking techniques, and electrospinning principles is provided, along with some of the many applications of these unique materials.