Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Gastritis-II: Pathophysiology01:17

Gastritis-II: Pathophysiology

1.8K
Gastritis is marked by disruption of the mucosal barrier that usually protects the stomach tissue from digestive juices and manifests in acute and chronic forms.
In acute gastritis, the gastric mucosa becomes swollen and red and undergoes superficial erosion. Superficial ulceration may lead to bleeding.
In chronic gastritis, persistent or repeated insults lead to chronic inflammatory changes and, eventually, thinning or atrophy of the gastric tissue.
Gastritis can stem from various causes, each...
1.8K
Gastritis-I: Introduction and Types01:27

Gastritis-I: Introduction and Types

3.5K
Gastritis, defined by the inflammation or irritation of the stomach lining or gastric mucosa, manifests in several distinct forms: acute, chronic, reactive, and a specific subtype known as autoimmune metaplastic atrophic gastritis.
Acute gastritis presents as a sudden inflammation triggered by various stressors to the stomach lining, such as exposure to corrosive agents, local irritants like aspirin and other NSAIDs, alcohol consumption, radiation therapy, physical trauma, severe burns, sepsis,...
3.5K
Gastritis III: Clinical Manifestations and Management01:23

Gastritis III: Clinical Manifestations and Management

1.8K
The clinical manifestations of gastritis can vary depending on the cause and type of gastritis, but some common symptoms may include the following.
Clinical manifestations of acute gastritis
The patient with acute gastritis may have a rapid onset of symptoms, such as epigastric pain or discomfort, dyspepsia, anorexia, hiccups, or nausea and vomiting, which can last from a few hours to a few days. Erosive or hemorrhagic gastritis may cause bleeding, which may manifest as blood in vomit or as...
1.8K
Peptic Ulcer Disease II: Pathophysiology01:28

Peptic Ulcer Disease II: Pathophysiology

2.9K
Peptic Ulcer Disease (PUD) is characterized by the development of ulcers in the stomach or duodenal mucosa. Its pathophysiology is complex, involving a balance between damaging and protective elements.
Damaging agents such as Helicobacter pylori, gastric acid, pepsin, and nonsteroidal anti-inflammatory drugs (NSAIDs) can weaken the mucosal defense, allowing hydrogen ions to infiltrate back and harm epithelial cells.
2.9K
Chronic Pancreatitis I: Introduction01:24

Chronic Pancreatitis I: Introduction

928
The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
928
Collagens are the Major Structural Proteins of ECM01:13

Collagens are the Major Structural Proteins of ECM

6.5K
Three main types of fibers are secreted by fibroblasts: collagen fibers, elastic fibers, and reticular fibers. Collagen fiber is made from fibrous protein subunits linked together to form a long, straight fiber. Collagen fibers, while flexible, have great tensile strength, resist stretching, and give ligaments and tendons their characteristic resilience and strength. These fibers hold connective tissues together, even during the body's movement.
Connective tissue proper includes loose...
6.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Tissue-based detection of macrophage-associated YAP1-positive material in human acute liver injury: an exploratory immunopathological biopsy series.

Diagnostic pathology·2026
Same author

Intercostal Electromyographic Responses to Multi-Site Chest Wall Vibration at an Optimal Frequency.

Respiratory physiology & neurobiology·2026
Same author

Urgent Resection of Hepatocellular Carcinoma With Intracardiac Extension Under Moderate Hypothermic Circulatory Arrest.

Interdisciplinary cardiovascular and thoracic surgery·2026
Same author

Emergence of norovirus GII.7 and predominance of recombinant strains in pediatric acute gastroenteritis in Japan, 2021-2024.

Archives of virology·2026
Same author

Co-Circulation and Mixed Infections of Classic and Melbourne Human Astroviruses Among Pediatric Acute Gastroenteritis Patients in Japan, 2018-2024.

Journal of medical virology·2026
Same author

Establishment of a novel deep learning-based method for gait analysis after peripheral nerve injury in pigs.

Regenerative therapy·2026

Related Experiment Video

Updated: Apr 16, 2026

Isolation of Lamina Propria Mononuclear Cells from Murine Colon Using Collagenase E
09:48

Isolation of Lamina Propria Mononuclear Cells from Murine Colon Using Collagenase E

Published on: September 26, 2019

16.9K

Collagenous gastritis: Review.

Kenya Kamimura1, Masaaki Kobayashi1, Yuichi Sato1

  • 1Kenya Kamimura, Masaaki Kobayashi, Yuichi Sato, Yutaka Aoyagi, Shuji Terai, Division of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences, Niigata University, Niigata 951-8510, Japan.

World Journal of Gastrointestinal Endoscopy
|March 20, 2015
PubMed
Summary

Collagenous gastritis, a rare condition with subepithelial collagen deposition, requires further study. Reviewing existing cases aims to improve diagnosis and develop effective treatments for this uncommon gastrointestinal disease.

Keywords:
Collagen depositionCollagenous colitisCollagenous gastritisNodularity

More Related Videos

Author Spotlight: Analyzing Fibrosis Development in Chronic Lung Allograft Rejection Using Picrosirius Red Staining in Mouse Models
04:42

Author Spotlight: Analyzing Fibrosis Development in Chronic Lung Allograft Rejection Using Picrosirius Red Staining in Mouse Models

Published on: March 21, 2025

1.6K
Three-Dimensional Collagen Matrix Scaffold Implantation as a Liver Regeneration Strategy
05:20

Three-Dimensional Collagen Matrix Scaffold Implantation as a Liver Regeneration Strategy

Published on: June 29, 2021

3.6K

Related Experiment Videos

Last Updated: Apr 16, 2026

Isolation of Lamina Propria Mononuclear Cells from Murine Colon Using Collagenase E
09:48

Isolation of Lamina Propria Mononuclear Cells from Murine Colon Using Collagenase E

Published on: September 26, 2019

16.9K
Author Spotlight: Analyzing Fibrosis Development in Chronic Lung Allograft Rejection Using Picrosirius Red Staining in Mouse Models
04:42

Author Spotlight: Analyzing Fibrosis Development in Chronic Lung Allograft Rejection Using Picrosirius Red Staining in Mouse Models

Published on: March 21, 2025

1.6K
Three-Dimensional Collagen Matrix Scaffold Implantation as a Liver Regeneration Strategy
05:20

Three-Dimensional Collagen Matrix Scaffold Implantation as a Liver Regeneration Strategy

Published on: June 29, 2021

3.6K

Area of Science:

  • Gastroenterology
  • Pathology
  • Rare Diseases

Background:

  • Collagenous gastritis is characterized by subepithelial collagen deposition (>10 μm) and lamina propria inflammation.
  • It shares histological features with collagenous colitis and collagenous sprue, considered part of a spectrum.
  • Unlike collagenous colitis, collagenous gastritis is exceptionally rare, with only 60 reported cases since 1989.

Purpose of the Study:

  • To review and summarize current knowledge on collagenous gastritis.
  • To highlight the need for improved diagnostic criteria and therapeutic strategies.
  • To consolidate information from case reports and series for better clinical understanding.

Main Methods:

  • Systematic review of published case reports and case series on collagenous gastritis.
  • Analysis of clinical characteristics, endoscopic findings, and histological features.
  • Evaluation of reported treatments and patient outcomes.

Main Results:

  • The review synthesizes data from limited case studies, detailing the rarity of the condition.
  • No definitive safe and effective treatments have been established through controlled trials.
  • Clinical presentation, diagnostic challenges, and treatment variability are highlighted.

Conclusions:

  • Further research and case reporting are crucial for establishing diagnostic standards for collagenous gastritis.
  • Development of standardized therapeutic strategies is needed for this rare gastrointestinal disorder.
  • Improved understanding will aid physicians in recognizing and managing collagenous gastritis, paving the way for future clinical trials.