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Updated: Apr 16, 2026

Improved Renal Denervation Mitigated Hypertension Induced by Angiotensin II Infusion
Published on: May 26, 2022
The path of least resistance to success in chronic hypertension?
Marvin H Eng1, Andrew J P Klein
1Department of Medicine, Division of Cardiology, University of Texas Health Sciences Center, San Antonio, Texas.
Abstract:
The ROX Coupler is a stented arterial-venous anastomosis intended for implantation in the external iliac artery and vein. Prior studies of the ROX Coupler show that it increases cardiac output, oxygen delivery, and decreases systemic vascular resistance, thereby lowering blood pressure. Clinical data for the ROX Coupler demonstrates significant reduction in blood pressure but proximal venous stenoses have been seen post-implantation requiring treatment.
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