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Complete genome sequence of Lysinibacillus varians GY32, a bacterium with filament-to-rod cell cycle
Chunjie Zhu1, Guoping Sun2, Guoping Zhao3
1School of Bioscience and Bioengineering, South China University of Technology, Guangzhou Higher Education Mega Centre, Panyu District, Guangzhou 510006, Guangdong, China Guangdong Provincial Key Laboratory of Microbial Culture Collection and Application, Guangdong Institute of Microbiology, 100 Xianlie Road, Yuexiu District, Guangzhou 510070, Guangdong, China State Key Laboratory of Applied Microbiology Southern China, 100 Xianlie Road, Yuexiu District, Guangzhou 510070, Guangdong, China.
Abstract:
The complete genome sequence of Lysinibacillus varians GY32 was determined to be 4,662,822 base pairs in a single circular chromosome. Genes in cell division, cell cycle, surface layer and cell wall synthesis are foundation of its unique cell morphology. The genome contains multiple clusters of transcriptional regulator, two-component system and sigma factors, providing the organism with the ability to regulate a filament-to-rod cell cycle progression. L. varians GY32 was, to our knowledge, the first bacterium with a filament-to-rod cell cycle to be sequenced and its annotated genome might provide new insights into our understanding of bacterial cell cycle regulation.
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