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Author Spotlight: Enhancing Coronary Artery Revascularization
Published on: September 15, 2023
Outcome of emergency coronary artery bypass grafting
Fausto Biancari1, Francesco Onorati2, Antonino S Rubino3
1Department of Surgery, Oulu University Hospital, Oulu, Finland.
Insights
Emergency coronary artery bypass grafting (CABG) outcomes were evaluated, showing satisfactory results despite risks. Significant variations in emergency CABG outcomes between hospitals highlight the need to analyze referral and treatment strategies.
Area of Science:
- Cardiovascular Surgery
- Thoracic Surgery
- Cardiac Surgery
Background:
- Emergency coronary artery bypass grafting (CABG) is a critical procedure for patients with acute cardiac conditions.
- Multicenter studies are essential to understand variations in outcomes and identify best practices.
Purpose of the Study:
- To evaluate the immediate and late outcomes of emergency coronary artery bypass grafting (CABG) in a multicenter setting.
- To identify predictors of in-hospital mortality and long-term survival after emergency CABG.
Main Methods:
- A multicenter, retrospective study involving 596 patients who underwent isolated, emergency CABG.
- Data were collected from four university hospitals.
Main Results:
- In-hospital mortality was 10.1% (pooled rate: 8.7%), with predictors including emergency CABG class, recent myocardial infarction, low ejection fraction, on-pump surgery, and participating center.
- One, three, and five-year survival rates were 86.4%, 81.6%, and 76.1%, respectively.
- Significant institutional differences in in-hospital mortality (2.8%–19.8%) and midterm survival were observed, likely due to variations in referral pathways and perioperative treatments.
Conclusions:
- Emergency CABG yields satisfactory outcomes despite inherent risks.
- Significant variations in outcomes between institutions necessitate further investigation into referral pathways and perioperative strategies.
- Optimizing treatment strategies is crucial for centers with suboptimal emergency CABG results.
Objectives:
The aim of this study was to evaluate the immediate and late outcome of emergency coronary artery bypass grafting (CABG) in a multicenter setting.
Design:
Multicenter, retrospective study.
Setting:
Four university hospitals.
Participants:
596 patients were included in this study.
Interventions:
Included patients underwent isolated, emergency CABG.
Measurements And Main Results:
Sixty patients (absolute rate: 10.1%, pooled rate: 8.7%) died during the in-hospital stay period. Increasing emergency CABG classes (p<0.0001), recent myocardial infarction (p=0.019), left ventricular ejection fraction≤30% (p=0.034), on-pump surgery (p=0.012), and participating centers (p<0.0001) were independent predictors of in-hospital mortality. Survival rates at 1, 3, and 5 years were 86.4%, 81.6%, and 76.1%, respectively. Extracorporeal membrane oxygenation was used in 6 patients and 3 of them (50.0%) survived the immediate postoperative period. Patient populations of participating centers differed significantly in most of baseline characteristics. The preoperative use of intra-aortic balloon pump (8% to 51%) and off-pump surgery (2.8% to 56.3%) varied significantly between institutions. In-hospital mortality (2.8%, 5.9%, 7.7% and 19.8%, p<0.0001), as well as midterm survival, significantly differed between institutions (at 3 years, 90.6%, 89.8%, 81.2%, and 67.2%, p<0.0001).
Conclusions:
The outcome after emergency CABG is satisfactory despite a significant operative risk. However, the results of emergency CABG significantly differed between the participating institutions, likely due to differences in the referral pathways and perioperative treatment strategies. Evaluation of these factors is crucial for implementation of treatment in centers with suboptimal results.
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