Related Experiment Video
Updated: Apr 16, 2026
In Vivo, Percutaneous, Needle Based, Optical Coherence Tomography of Renal Masses
Published on: March 30, 2015
Utility of semiquantitative strain elastography for differentiation between benign and malignant solid renal masses
Mehmet Ruhi Onur1, Ahmet Kursad Poyraz2, Zulkif Bozgeyik2
1Department of Radiology, Faculty of Medicine, University of Firat, Elazig, Turkey. ruhionur@yahoo.com.
Objectives:
The aim of this study was to determine the role of semiquantitative strain elastography for differentiation of benign and malignant solid renal masses.
Methods:
Seventy-one patients with solid renal masses were prospectively examined with ultrasound elastography after grayscale sonography. Strain elastography was used to compare the stiffness of the renal masses and renal parenchyma. The ratio of strain in a renal mass and nearby renal parenchyma was defined as the strain index value. Mean strain index values for benign masses (n = 29; 24 angiomyolipomas and 5 oncocytomas) and malignant masses (n = 42; 34 renal cell carcinomas, 4 transitional cell carcinomas, 3 metastases, and 1 lymphoma) and mean strain index values for angiomyolipomas and renal cell carcinomas were compared.
Results:
There were no significant differences in the mean age of the patients, mean diameter of the masses, and mean probe-mass distance between benign and malignant groups. The mean strain index value ± SD for malignant masses (4.05 ± 2.17) was significantly higher than the value for benign masses (1.43 ± 0.94; P < .05). The mean strain index value for renal cell carcinomas (4.30 ± 2.27) was significantly higher than the value for angiomyolipomas (1.28 ± 1.01; P < .0001).
Conclusions:
Strain elastography may be a useful imaging technique for differentiation between benign and malignant solid renal masses.
