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Electrolytic Inferior Vena Cava Model EIM of Venous Thrombosis
Published on: July 12, 2011
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Isolated cortical vein thrombosis: case series.
Ranjodh Singh1, William P Cope1, Zhiping Zhou1
1Departments of 1 Neurological Surgery and.
Journal of Neurosurgery
|March 21, 2015
Summary
Isolated cortical vein thrombosis (ICVT) is rare but can cause severe brain damage. Early diagnosis using MRI, particularly susceptibility-weighted imaging, is crucial for effective treatment with anticoagulation therapy.
Area of Science:
- Neurology
- Radiology
- Vascular Medicine
Background:
- Isolated cortical vein thrombosis (ICVT) is an uncommon cause of cerebral infarction, accounting for less than 1% of cases.
- Prompt diagnosis of ICVT is critical to prevent irreversible parenchymal damage.
Purpose of the Study:
- To present clinical and radiological findings in 7 patients with ICVT.
- To identify key risk factors and optimal imaging modalities for timely ICVT diagnosis.
Main Methods:
- Retrospective review of patients with CT and MRI findings consistent with ICVT.
- Inclusion criteria: ICVT diagnosis between January 2011 and June 2014.
Main Results:
- Seven patients (5 females, 2 males; age 11 months-34 years) were included.
- Common symptoms: headaches (4) and seizures (3). Common comorbidities: hypercoagulable states (4) and intracranial hypotension (3).
- MRI confirmed diagnosis in all 7 patients; CT suggested it in 4. Anticoagulation therapy led to complete symptom resolution in 5 patients.
Conclusions:
- Adult females were the majority, aligning with existing literature.
- Hypercoagulable states and intracranial hypotension were significant risk factors.
- Intraparenchymal involvement was common, manifesting as edema, hemorrhage, or infarction. Susceptibility-weighted imaging demonstrated the highest sensitivity for ICVT detection.
Keywords:
CTA = CT angiographyCTV = CT venographyDWI = diffusion-weighted imagingGRE = gradient-recalled echoICVT = isolated cortical vein thrombosisIPH = intraparenchymal hemorrhageMRV = MR venographySAH = subarachnoid hemorrhageSDH = subdural hemorrhageSPGR = spoiled gradient recalled echoSWI = susceptibility-weighted imagingintraparenchymal hemorrhageisolated cortical vein thrombosismagnetic resonance imagingsusceptibility-weighted imagingvascular disordersvenous infarction
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