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Induction of Invasive Transitional Cell Bladder Carcinoma in Immune Intact Human MUC1 Transgenic Mice: A Model for Immunotherapy Development
Published on: October 30, 2013
[Superficial bladder cancer: Transurethral resection and instillation therapy]
1Klinik und Poliklinik für Urologie, Uroonkologie und Kinderurologie, Urologische Universitätsklinik Essen, Universitätsklinikum Essen, Hufelandstraße 55, 45122, Essen, Deutschland, Marcus.Schenck@uni-due.de.
Bladder cancer, the fifth most common male cancer, is rising globally. Transurethral resection (TUR-B) effectively removes surface tumors, with newer techniques like transurethral resection in saline (TURIS) enhancing safety despite potential complications.
Area of Science:
- Urology
- Oncology
- Surgical Technology
Context:
- Bladder cancer incidence is increasing in developed nations, particularly among men, ranking as the fifth most common cancer.
- Surface-growing bladder tumors, comprising 80% of cases, are amenable to endoscopic removal via transurethral resection (TUR-B).
- Advancements in endoscopic equipment, including video imaging and bipolar resection (TURIS), have improved the safety of these procedures.
Purpose:
- To review the efficacy and safety of endoscopic transurethral resection (TUR-B) for bladder tumors.
- To highlight the benefits of modern techniques like transurethral resection in saline (TURIS) in improving patient outcomes.
- To discuss potential intra- and postoperative complications associated with transurethral electrosurgery of bladder tumors.
Summary:
- Transurethral resection (TUR-B) is a primary treatment for superficial bladder tumors, which constitute the majority of cases.
- Modern endoscopic techniques, such as transurethral resection in saline (TURIS), offer enhanced safety profiles due to technological improvements.
- Despite advancements, the risk of complications during and after transurethral electrosurgery for bladder tumors remains a consideration.
Impact:
- Improved understanding of current bladder cancer treatment modalities.
- Guidance on selecting appropriate endoscopic techniques for bladder tumor resection.
- Awareness of potential risks and complications, facilitating better patient management and informed consent.
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