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Updated: Apr 16, 2026
Murine Excisional Wound Healing Model and Histological Morphometric Wound Analysis
Published on: August 21, 2020
Is histological examination necessary when excising a pilonidal cyst?
Styliani N Parpoudi1, Dimitrios S Kyziridis1, Dimitrios Ch Patridas1
14th Department of General Surgery, General Hospital "G. Papanikolaou", Aristotle University of Thessaloniki, Thessaloniki, Greece.
Background:
Pilonidal disease is a common inflammatory condition mostly affecting young males. Malignant degeneration of a pilonidal cyst is rare, with incidence estimated at 0.1%. The most common type is squamous cell carcinoma and the treatment of choice remains en block resection of the lesion.
Case Report:
We present the case of a patient with locally advanced squamous cell carcinoma arising in a pilonidal cyst, due to misdiagnosis of the disease during his first treatment.
Conclusions:
Detailed histological examination of all excised pilonidal cyst lesions is essential and any histological suspicion should prompt a wider excision.
