Related Experiment Video
Updated: Apr 16, 2026
Development and Functionalization of Electrolyte-Gated Graphene Field-Effect Transistor for Biomarker Detection
Published on: February 1, 2022
A novel graphene oxide-based fluorescent nanosensor for selective detection of Fe(3+) with a wide linear
Liang He1, Jianna Li2, John H Xin1
1Institute of Textiles and Clothing, The Hong Kong Polytechnic University, Hung Hom, Hong Kong, P.R. China.
Abstract:
A graphene oxide-based fluorescent nanosensor AGO has been designed and synthesized by covalent grafting allylamine onto GO surface. In aqueous media, AGO displays a highly selective and sensitive discrimination of Fe(3+) from Fe(2+) and other metal ions through electron transfer-induced fluorescence quenching. The quenching of AGO fluorescence is linearly proportional to Fe(3+) concentration in a wide range of 0-120 μM (correlation coefficient R(2)=0.9994). Moreover, AGO can be used to construct a combinational three-input logic gate to discriminate Fe(3+) and Fe(2+). The logic gate works well in intracellular fluorescence imaging, which shows a potential as a promising platform for biosensing analysis.
