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Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus
Published on: May 16, 2025
Facial angioedema and systemic lupus erythematosus: case report
Daniel Bienstock1, Louis Mandel2
1Resident, Department of Oral and Maxillofacial Surgery, New York-Presbyterian Medical Center (Columbia Campus), New York, NY.
Abstract:
Non-medication-related acquired deficiencies of C1 esterase inhibitor (C1-INH) can cause the facial acquired angioedema (AAE) seen in systemic lupus erythematosus (SLE). The defect can originate from a lymphoproliferative disease (LPD) that catabolizes C1-INH or from circulating antibodies that inactivate C1-INH. This report describes a third and rare variety of facial AAE originating in SLE in which there was no LPD or circulating antibodies to impede C1-INH activity.
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