Doctors' awareness concerning primary immunodeficiencies in Brazil.

Area of Science:

• Immunology
• Genetics
• Medical Education

Background:

• Primary immunodeficiencies (PIDs) are a diverse group of genetic disorders.
• Delayed diagnosis of PIDs is often attributed to insufficient physician awareness.
• This study evaluated physician awareness of PIDs in Brazil.

Purpose of the Study:

• To assess the level of medical awareness regarding primary immunodeficiencies (PIDs) among physicians in Brazil.
• To identify potential gaps in knowledge that contribute to diagnostic delays for PIDs.

Main Methods:

• A nationwide survey of physicians in general hospitals across Brazil.
• A 14-item questionnaire was administered, including 25 clinical scenarios to assess PID knowledge.
• A scoring system was developed based on the accuracy of responses to clinical situations.

Main Results:

• 4026 physicians participated: 1628 pediatricians, 1436 clinicians, and 962 surgeons.
• Only 40.3% of physicians participated in the immunological evaluation of patients on frequent antibiotics.
• 77% were unfamiliar with PID warning signs, and the average correct answer score was 48.08%.

Conclusions:

• A significant lack of awareness regarding PIDs exists among Brazilian physicians, including pediatricians.
• Despite educational efforts, awareness remains insufficient, highlighting the need for enhanced PID education.
• Improving medical community awareness is crucial for better PID recognition and patient outcomes.