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Updated: Apr 15, 2026

Simultaneous Laryngopharyngeal and Conventional Esophageal pH Monitoring
Published on: December 14, 2020
[Level of pepsinogen in patients with gastroesophageal reflux disease]
Abstract:
We studied level of pepsinogen I and II in blood serum in 50 patients with erosive form of gastroesophageal reflux disease. Increasing concentrations of pepsinogen in 2.1 times and increasing the ratio of pepsinogen I to pepsinogen II in 32% of patients was detected. Which was associated with a higher degree gradation of erosive lesions of the esophagus and acid reflux prevalence with 2.0-2.99 pH range. Higher concentrations of pepsinogen II in serum was diagnosed in 20% of patients, and the results of daily pH monitoring in lower part of esophagus have been registered in them as acidic and alkaline refluxes.
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