Pregnancy outcome in proteinuria-onset and hypertension-onset preeclampsia

To evaluate pregnancy outcome in preeclampsia (PE), according to the timing of onset of proteinuria and hypertension.

Preeclamptic women were retrospectively divided into proteinuria-onset and hypertension-onset PE according to the first symptom. Maternal and perinatal outcome were assessed in both the groups.

One hundred and ninety five single pregnancies complicated by PE were included. According to the first symptom, they were divided into two groups: proteinuria-onset PE (n = 49, 25.1%) and hypertension-onset PE (n = 146, 74.9%). Pregnancy and neonatal outcome was significantly worse in proteinuria-onset PE.

Proteinuria-onset PE is associated with an increased risk of adverse pregnancy outcome than hypertension-onset PE.