Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Asymmetric Lipid Bilayer01:35

Asymmetric Lipid Bilayer

11.2K
Biological membranes show uneven distribution of different types of lipids in the inner and outer layers, resulting in transverse asymmetric membranes. The treatment of the erythrocyte membrane with the enzyme phospholipase confirmed the asymmetric nature of the lipid bilayer. The enzyme hydrolyzes lipids into fatty acids and hydrophilic groups. The phospholipase acts only on the outer layer of the membrane, while the inner layer remains intact. The phospholipase treatment resulted in 80%...
11.2K
Fluid Mosaic Model01:19

Fluid Mosaic Model

20.3K
Scientists identified the plasma membrane in the 1890s and its principal chemical components (lipids and proteins) by 1915. The model for plasma membrane structure, proposed in 1935 by Hugh Davson and James Danielli, was the first model to be widely accepted in the scientific community. The model was based on the plasma membrane's "railroad track" appearance in early electron micrographs. Davson and Danielli theorized that the plasma membrane's structure resembled a sandwich...
20.3K
Assembly of the Lipid Bilayer in the ER01:28

Assembly of the Lipid Bilayer in the ER

4.6K
Biological membranes are more than just a barrier separating cell cytoplasm from the outside environment. They are highly dynamic and help maintain the integrity and physiological stability of the cells as well as membrane-bound organelles. Membranes also play vital roles in cell-to-cell and intracellular communication.
A large chunk of any biological membrane is composed of phospholipids. These lipids have a heterogeneous distribution across different subcellular organelles and even between...
4.6K
Membrane Fluidity01:26

Membrane Fluidity

18.3K
Membrane fluidity is explained by the fluid mosaic model of the cell membrane, which describes the plasma membrane structure as a mosaic of components—including phospholipids, cholesterol, proteins, and carbohydrates—that gives the membrane a fluid character.
Mosaic nature of the membrane
The mosaic characteristic of the membrane helps the plasma membrane remain fluid. The integral proteins and lipids exist as separate but loosely-attached molecules in the membrane. The membrane is...
18.3K
Membrane Domains01:18

Membrane Domains

8.4K
The membrane domains concentrate specific lipids and proteins at one place within the membrane, which helps in cell signaling, adhesion, and other critical cellular processes. These domains can differ in size, composition, function, and lifespan.
Protein Domains
The membrane comprises a group of distinct proteins responsible for carrying out a cell's specific function. For example, the plasma membrane of the human sperm, or a single germ cell, contains a unique set of proteins in the...
8.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Probing radiation forces acting on acoustic bubbles using digital in-line holography.

Ultrasonics sonochemistry·2026
Same author

Antibacterial Properties of Low Silver Content ZrCu-Based PVD Thin Film Metallic Glasses: Effect of a Femtosecond Laser Texturing.

ACS applied materials & interfaces·2026
Same author

Global characterization of Dictyostelium discoideum gene and protein expression changes under hypoxic conditions.

BMC genomics·2025
Same author

Impact of focused ultrasound on the cellular network of liver tissue: a new perspective for thermal lesion detection.

Physics in medicine and biology·2025
Same author

Statistical and mechanical analysis of multi-pseudopodial locomotion in a testate amoeba, Arcella sp.

Proceedings of the Japan Academy. Series B, Physical and biological sciences·2025
Same author

Dictyostelium discoideum chemotaxis is altered by hypoxia to orient streaming toward higher oxygen levels.

BMC molecular and cell biology·2025
Same journal

Correction: Effect of external salt solution concentration on carboxyl dissociation degree (<i>α</i>) and p<i>K</i><sub>a</sub> of weak polyelectrolyte membranes for sustainable technologies.

Soft matter·2026
Same journal

Anomalous dewetting dynamics in active entangled polymer films: flexible chains.

Soft matter·2026
Same journal

Electrorheology of the suspensions of oblate poly(ionic liquid) ellipsoids.

Soft matter·2026
Same journal

Nanopore sequencing with proteins: synchronization and dischronization of molecular dynamics simulations with laboratory and industrial developments.

Soft matter·2026
Same journal

Catanionics from biosurfactants and regular surfactants: miscibility and structure.

Soft matter·2026
Same journal

Adhesives with a thickness smaller than the fractocohesive length enhance adhesion.

Soft matter·2026
See all related articles

Related Experiment Video

Updated: Apr 15, 2026

Lipid Bilayer Experiments with Contact Bubble Bilayers for Patch-Clampers
07:18

Lipid Bilayer Experiments with Contact Bubble Bilayers for Patch-Clampers

Published on: January 16, 2019

10.3K

Jumping acoustic bubbles on lipid bilayers.

Christelle Der Loughian1, Pauline Muleki Seya, Christophe Pirat

  • 1Institut Lumière Matière, UMR5306 Université Lyon 1-CNRS, Université de Lyon 69622, Villeurbanne cedex, France. jean-paul.rieu@univ-lyon1.fr.

Soft Matter
|March 24, 2015
PubMed
Summary
This summary is machine-generated.

Microbubbles jumping on lipid bilayers during sonoporation create unique membrane patterns. This study models these interactions, explaining lipid exchange between bubbles and membranes.

More Related Videos

Author Spotlight: Advancing Cell Membrane Biophysics - Exploring Interactions and Challenges Through Experimental and Computational Approaches
07:31

Author Spotlight: Advancing Cell Membrane Biophysics - Exploring Interactions and Challenges Through Experimental and Computational Approaches

Published on: September 1, 2023

3.5K
Neutron Spin Echo Spectroscopy as a Unique Probe for Lipid Membrane Dynamics and Membrane-Protein Interactions
10:02

Neutron Spin Echo Spectroscopy as a Unique Probe for Lipid Membrane Dynamics and Membrane-Protein Interactions

Published on: May 27, 2021

4.6K

Related Experiment Videos

Last Updated: Apr 15, 2026

Lipid Bilayer Experiments with Contact Bubble Bilayers for Patch-Clampers
07:18

Lipid Bilayer Experiments with Contact Bubble Bilayers for Patch-Clampers

Published on: January 16, 2019

10.3K
Author Spotlight: Advancing Cell Membrane Biophysics - Exploring Interactions and Challenges Through Experimental and Computational Approaches
07:31

Author Spotlight: Advancing Cell Membrane Biophysics - Exploring Interactions and Challenges Through Experimental and Computational Approaches

Published on: September 1, 2023

3.5K
Neutron Spin Echo Spectroscopy as a Unique Probe for Lipid Membrane Dynamics and Membrane-Protein Interactions
10:02

Neutron Spin Echo Spectroscopy as a Unique Probe for Lipid Membrane Dynamics and Membrane-Protein Interactions

Published on: May 27, 2021

4.6K

Area of Science:

  • Biophysics
  • Materials Science

Background:

  • Supported lipid bilayers serve as models for biological membranes.
  • Ultrasound-induced microbubbles are used in sonoporation.

Purpose of the Study:

  • Investigate interactions between microbubbles and supported lipid bilayers under ultrasound.
  • Propose a model for microbubble dynamics and membrane alteration.

Main Methods:

  • Utilized supported lipid bilayers as a model system.
  • Observed microbubble-bilayer interactions using varying time and space resolutions.

Main Results:

  • Discovered a unique phenomenon of microbubbles 'jumping' on the bilayer surface.
  • Observed the formation of a 'necklace' pattern of membrane alteration.
  • Proposed a model incorporating van der Waals, acoustic, and hydrodynamic forces.

Conclusions:

  • The proposed model explains the observed jumping phenomenon and associated lipid exchanges.
  • This research provides insights into the mechanisms of ultrasound-induced membrane modification.