Structure-based hybridization, synthesis and biological evaluation of novel tetracyclic heterocyclic azathioxanthone

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Functionalized Spirocyclic Heterocycle Synthesis and Cytotoxicity Assay
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Tsung-Chih Chen1, Chia-Lun Wu2, Chia-Chung Lee1

  • 1Graduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei 110, Taiwan; Graduate Institute of Life Sciences, National Defense Medical Center, Taipei 114, Taiwan.

European Journal of Medicinal Chemistry
|March 24, 2015
PubMed

Keywords:
AzathioxanthonesCytostatic and cytotoxic activitiesMTT assayNCI-60 human tumor cell linesTopoisomerase assays

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