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Secondary Lymphoid Organs

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[Mucosal lymphomatoid papulosis: 2 cases].

L Benslama¹, C V Andre², F Charlotte³

¹Service de stomatologie et chirurgie maxillo-faciale, AP-HP, DHU Fast, GH Pitié-Salpêtrière-Charles-Foix, 75013 Paris, France; UMR 8256 B2A, Sorbonne universités, UPMC université Paris 06, 75005 Paris, France.

Revue De Stomatologie, De Chirurgie Maxillo-Faciale Et De Chirurgie Orale

|March 25, 2015

Summary

This study presents two rare cases of oral lymphomatoid papulosis (LP) without skin lesions. These findings expand the known clinical presentations of this CD30+ cutaneous lympho-proliferative disorder.

Keywords:

Lymphomatoid papulosis Papulose lymphomatoïde

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Area of Science:

Dermatology
Oncology
Pathology

Background:

Lymphomatoid Papulosis (LP) is a CD30+ cutaneous lympho-proliferative disorder.
Mucosal involvement in LP is rare, with limited documented cases.
Existing literature primarily reports oral LP with concurrent skin lesions.

Observation:

Two adult women presented with isolated, painful oral ulcerations.
Lesions occurred on the maxillary tuberosity and inner cheek.
Biopsies confirmed Type A Lymphomatoid Papulosis via immunohistochemistry.

Findings:

The reported oral LP cases occurred without any cutaneous manifestations.
Maxillary tuberosity and inner cheek involvement are novel presentations.
Both patients' lesions resolved spontaneously.

Implications:

This expands the differential diagnosis for isolated oral ulcerations.
Highlights the potential for LP to present solely in the oral mucosa.
Suggests spontaneous resolution is possible even in oral presentations.