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Evalution of Serum Lipid Profiles in Turkish Children Aged Two to Eighteen Years

D Toprak1, A Bukulmez2, N Dogan3

  • 1Sisli Etfal Training and Research Hospital, Family Medicine Clinics, Istanbul, Turkey. dilekt66@yahoo.com.

The West Indian Medical Journal
|March 25, 2015
PubMed

Insights

Dyslipidemia affects over a third of children, with high very low-density lipoprotein cholesterol and low high-density lipoprotein cholesterol linked to child percentiles. Early detection in childhood is crucial for preventing cardiovascular risks.

Area of Science:

  • Pediatric Endocrinology
  • Cardiovascular Health
  • Epidemiology

Background:

  • Dyslipidemia in childhood is a growing concern.
  • Early identification is key to preventing future cardiovascular disease.
  • Sociodemographic factors may influence lipid profiles in children.

Purpose of the Study:

  • To assess dyslipidemia prevalence in children.
  • To investigate the relationship between dyslipidemia and various sociodemographic factors.
  • To establish baseline lipid profiles for early cardiovascular risk assessment.

Main Methods:

  • Cross-sectional epidemiologic study of 285 children (2-18 years).
  • Assessment of lipid profiles, including total cholesterol, triglycerides, VLDL-C, and HDL-C.
  • Evaluation of correlations between lipid levels and age, gender, percentiles, maternal education, breastfeeding duration, and residence.

Main Results:

  • Overall dyslipidemia prevalence was 37.4%.
  • Elevated VLDL-C and low HDL-C were associated with child percentiles (p=0.006, p=0.03).
  • Gender influenced VLDL-C levels, with girls having higher levels (p=0.04). High triglycerides were observed in 25.3% and low HDL-C in 18.2%.

Conclusions:

  • While overall dyslipidemia parameters were not excessively high in the studied region, vigilance is necessary.
  • Periodic health checks are recommended for early detection of dyslipidemia in children.
  • Proactive management in childhood is essential for mitigating long-term cardiovascular risks.
Abstract

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